Utilize este identificador para referenciar este registo: https://recil.grupolusofona.pt/handle/10437/4654
Título: Autosomal dominant polycystic kidney disease in hemodialysis patients in southern Brazil
Outros títulos: Doença renal policística autossômica dominante em pacientes em hemodiálise no sul do Brasil
Autores: Alves, Everton Fernando
Tsuneto, Luiza Tamie
Pelloso, Sandra Marisa
Torres, Paulo Roberto Aranha
Otto, Guido Luis Gomes
Silva, Adaelson Alves
Obregon, José Miguel Viscarra
Silva, Leticia Nicoletti
Carvalho, Maria Dalva de Barros
Palavras-chave: DIÁLISE
EPIDEMIOLOGIA
FALÊNCIA RENAL CRÓNICA
INSUFICIÊNCIA RENAL CRÓNICA
RIM POLICÍSTICO AUTOSSÓMICO DOMINANTE
DIALYSIS
EPIDEMIOLOGY
CHRONIC KIDNEY FAILURE
POLYCYSTIC KIDNEY AUTOSOMAL DOMINANT
RENAL REPLACEMENT THERAPY
Data: 10-Mar-2014
Editora: Sociedade Brasileira de Nefrologia
Citação: Alves Everton Fernando, Tsuneto Luiza Tamie, Pelloso Sandra Marisa, Torres Paulo Roberto Aranha, Otto Guido Luis Gomes, Silva Adaelson Alves et al . Doenca renal policistica autossomica dominante em pacientes em hemodialise no sul do Brasil. J Bras Nefrol 2014; 36(1):18-25.
Resumo: Introduction: Autosomal dominant polycystic kidney disease is the most common hereditary renal disease in humans. Objective: To examine the prevalence, clinical and laboratory characteristics of patients with polycystic kidneys and relate disease manifestations by gender. Methods: This was an observational and retrospective study. All the medical records of patients with polycystic kidneys who initiated hemodialysis between 1995 and 2012, in four centers that treat patients of the coverage area of the 15th regional health Paraná (Brazil), were analyzed. Results: The study included 48 patients with polycystic kidneys, the primary cause of stage 5 CKD. Disease prevalence was one in 10,912 people. The average age of dialysis initiation was 50.7 years and the follow-up time on dialysis until transplantation (36.5 months) was lower among men. Hypertension was the most frequent diagnosis in 73% of patients, predominantly in women (51.4%). The liver cyst was the most frequent extrarenal manifestations in men (60.0%). The death occurred in 10.4% of patients using hemodialysis, and 60% of men. The class of antihypertensive drug used was that acts on the renin-angiotensin system with higher frequency of use among women (53.3%). The post-dialysis urea was significantly higher in men. Conclusion: The prevalence of the disease is low among hemodialysis patients in southern Brazil. The differences observed between genders, with the exception of the post-dialysis urea, were not significant. The findings are different from those reported in North America and Europe.
URI: http://hdl.handle.net/10437/4654
ISSN: 0101-2800
Aparece nas colecções:Revista Lusófona de Ciências Aeronáuticas nº 01 (2007)

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