Social perception gaze patterns, symptom severity and resting brain function measured using Arterial Spin Labelling

DSpace/Manakin Repository

Social perception gaze patterns, symptom severity and resting brain function measured using Arterial Spin Labelling

Show simple item record

dc.contributor.author Diamandis, L.
dc.contributor.author Saitovitch, A.
dc.contributor.author Lemaitre, H.
dc.contributor.author Grevent, David
dc.contributor.author Chabane, N.
dc.contributor.author Phillipe, A.
dc.contributor.author Brunelle, F.
dc.contributor.author Boddaert, N.
dc.contributor.author Zilbovicius, M.
dc.date.accessioned 2012-04-10T10:39:11Z
dc.date.available 2012-04-10T10:39:11Z
dc.date.issued 2012
dc.identifier.issn 1647-7677
dc.identifier.uri http://hdl.handle.net/10437/2317
dc.description.abstract Autistic spectrum disorder (ASD) is characterised by qualitative alterations in reciprocal social interactions. Some recent studies show alterations in gaze patterns during social perception and rest-functional abnormalities in the ‘social brain network’. This study investigated: i) social perception gaze patterns in children with ASD and controls, ii) the relationship between autism clinical severity and social perception gaze patterns, iii) the relationship between resting cerebral blood flow (rCBF) and social perception gaze patterns. Methods: Nine children with ASD and 9 children with typical development were studied. Eye-tracking was used to detect gaze patterns during presentation of stimuli depicting social scenes. Autism clinical severity was established using the Autism Diagnostic Interview Revised (ADI-R). Arterial spin labelling MRI was used to quantify rCBF. Results: The ASD group looked less at social regions and more at non-social regions than controls. No significant correlation was found between ASD clinical severity and social perception gaze patterns. In the ASD group, gaze behaviour was related to rCBF in the temporal lobe regions at trend level. Positive correlations were found between temporal rCBF and gaze to the face region, while negative correlations were found between temporal rCBF and gaze to non-social regions. Conclusions: These preliminary results suggest that social perception gaze patterns are altered in children with ASD, and could be related to temporal rCBF. pt
dc.format application/pdf
dc.language.iso eng pt
dc.rights openAccess
dc.subject AUTISMO pt
dc.subject EYE TRACKING en
dc.subject NEUROCIÊNCIAS pt
dc.subject AUTISM en
dc.subject NEUROSCIENCES en
dc.title Social perception gaze patterns, symptom severity and resting brain function measured using Arterial Spin Labelling pt
dc.type article pt


Files in this item

Files Size Format View
Social_perception_gaze_patterns.pdf 622.0Kb PDF View/Open

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account